发明名称 |
Method of modifying dissolution rate of particles by addition of hydrophobic nanoparticles |
摘要 |
Method of modifying dissolution rate of a plurality of particles in an aqueous-based solvent by adding hydrophobic surface modified nanoparticles to the plurality of particles, and exposing the plurality of particles to the aqueous-based solvent. |
申请公布号 |
US8951541(B2) |
申请公布日期 |
2015.02.10 |
申请号 |
US201113811854 |
申请日期 |
2011.09.28 |
申请人 |
3M Innovative Properties Company |
发明人 |
Baran, Jr. Jimmie R.;Sykora Haeen;Everman Rebecca L. A. |
分类号 |
A61K9/14;B82Y30/00 |
主分类号 |
A61K9/14 |
代理机构 |
|
代理人 |
Kokko Kent S. |
主权项 |
1. A method of increasing the dissolution rate of a plurality of particles, the method comprising:
providing a plurality of particles, the particles having a solubility in an aqueous-based solvent; adding hydrophobic surface modified nanoparticles; and exposing the plurality of particles to the aqueous-based solvent, wherein the plurality of particles combined with the hydrophobic surface modified nanoparticles have a modified dissolution rate in the aqueous-based solvent relative to a dissolution rate of the plurality of particles in the aqueous-based solvent without the presence of hydrophobic surface modified nanoparticles. |
地址 |
St. Paul MN US |