发明名称 Method of modifying dissolution rate of particles by addition of hydrophobic nanoparticles
摘要 Method of modifying dissolution rate of a plurality of particles in an aqueous-based solvent by adding hydrophobic surface modified nanoparticles to the plurality of particles, and exposing the plurality of particles to the aqueous-based solvent.
申请公布号 US8951541(B2) 申请公布日期 2015.02.10
申请号 US201113811854 申请日期 2011.09.28
申请人 3M Innovative Properties Company 发明人 Baran, Jr. Jimmie R.;Sykora Haeen;Everman Rebecca L. A.
分类号 A61K9/14;B82Y30/00 主分类号 A61K9/14
代理机构 代理人 Kokko Kent S.
主权项 1. A method of increasing the dissolution rate of a plurality of particles, the method comprising: providing a plurality of particles, the particles having a solubility in an aqueous-based solvent; adding hydrophobic surface modified nanoparticles; and exposing the plurality of particles to the aqueous-based solvent, wherein the plurality of particles combined with the hydrophobic surface modified nanoparticles have a modified dissolution rate in the aqueous-based solvent relative to a dissolution rate of the plurality of particles in the aqueous-based solvent without the presence of hydrophobic surface modified nanoparticles.
地址 St. Paul MN US