Process for preparing products comprising stabilised actives and compositions comprising same

摘要

The present invention broadly relates to a process for preparing products comprising active components, and in particular biological materials, wherein the active components are stabilized. The invention further relates to compositions comprising the products, and in particular compositions comprising therapeutic biological materials.

主权项

1. A process for preparing a product comprising at least one active component, the process comprising:
(i) providing a coating liquid comprising the at least one active component, a saccharide and a water-miscible solvent; (ii) providing particles comprising one or more water-soluble gel-forming compounds; (iii) fluidising the particles within a processing chamber of an apparatus in such a manner that the particles move in an upward direction within the chamber in a helical path; (iv) spraying the coating liquid onto the particles so as to provide coated particles; (v) allowing the coated particles to dry.