COMPOSTOS 2-(2-OXOINDOLINA-3-ILIDENO)METIL-5-(2-HIDRÓXI-3-MORFOLI N-4-IL-PROPIL)-6,7-DI-HIDRO-1H-PIRROL[3,2-C]PIRIDINA-4(5H)- ONA E USO COMO INIBIDORES DE PROTEÍNOQUINASE

摘要

Pyrrolo[3,2-c]pyridine-4-one-2-indolinone compounds, especially 2-(2-oxoindoline-3-ylidene)methyl-5-(2-hydroxy-3-morpholin-4-yl-propyl)-6,7-dihyd ro-1H-pyrrol[3,2-c]pyridine-4(5H)-one compounds. Their preparation and pharmaceutical composition, and pharmaceutical use as protein kinase inhibitors.