| 发明名称 |
BRIDGED SPIRO[2,4]HEPTANE DERIVATIVES AS ALX AND/OR FPRL2 RECEPTOR AGONISTS |
| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to bridged spiro[2.4]heptane derivatives of formula(I), wherein W means -CHCH- or -CH=CH-; Z means -C(O)NR-* or -CHNRC(O)-*, Y means a bond or (C-C)alkane diyl group, R-Rare those as specified in the description, to preparing and using them as ALX and/or FPRL2 receptor agonists applicable for treating inflammatory and obstructive respiratory diseases.EFFECT: preparing the compositions for treating the inflammatory and obstructive respiratory diseases.14 cl, 1 tbl, 422 ex |
| 申请公布号 |
RU2540274(C2) |
申请公布日期 |
2015.02.10 |
| 申请号 |
RU20110151277 |
申请日期 |
2010.05.17 |
| 申请人 |
AKTELION FARMAS'JUTIKLZ LTD |
发明人 |
DANIEL' BUR;OLIV'E KORMENBEF;SIL'VENE KREN;KORINNA GRISOSTOMI;KSAV'ER LEROJ;SIL'V'JA RISHAR-BIL'DSHTAJN |
| 分类号 |
C07C233/58;A61K31/40;A61K31/426;A61K31/427;A61K31/44;A61P9/00;A61P11/00;A61P29/00;C07C233/60;C07C233/63;C07D207/09;C07D211/26;C07D213/40;C07D231/12;C07D233/64;C07D235/14;C07D239/30;C07D249/08;C07D277/28;C07D277/62;C07D307/52;C07D319/12 |
主分类号 |
C07C233/58 |
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