发明名称 Antibody against mucin 1 (MUC1) protein and use of same
摘要 The present invention provides means and a method assuring the effectiveness of early diagnosis of cancers including gastric cancers. Specifically, the present invention provides an antibody, which is prepared using, as an antigen, (a) a peptide comprising at least contiguous amino acids at positions 69 to 75 in the amino acid sequence of SEQ ID NO: 2, or (b) a peptide consisting of an amino acid sequence in which one or several amino acids are deleted, substituted or added in at least contiguous amino acids at positions 69 to 75 in the amino acid sequence of SEQ ID NO: 2, and having the antigenicity of human MUC1 protein, and which is reactive with human mucin 1 (MUC1) protein.
申请公布号 US8951526(B2) 申请公布日期 2015.02.10
申请号 US201113577841 申请日期 2011.02.10
申请人 Kagoshima University 发明人 Yonezawa Suguru
分类号 C07K16/30;G01N33/574;C07K14/47 主分类号 C07K16/30
代理机构 Lucas & Mercanti, LLP 代理人 Lucas & Mercanti, LLP
主权项 1. An isolated antibody that is produced by hybridoma cell line MUC1-014E, deposited as accession number NITE BP-867.
地址 Kagoshima-Shi, Kagoshima JP