发明名称 |
NOVEL COMPOUND HAVING ABILITY TO INHIBIT 11B-HSD1 ENZYME OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT |
摘要 |
The present invention relates to a novel compound or a pharmaceutically acceptable salt thereof inhibiting 11B-HSD1 enzyme activity, a preparation method of the same, and a pharmaceutical composition comprising the same as an active ingredient. Since the compound of the present invention selectively inhibits the activity of 11B-HSD1 (11B-Hydroxysteroid dehydrogenase type 1), the compound of the invention can be effectively used as a therapeutic agent for the treatment of diseases caused by the over-activation of 11B-HSD1 such as non-insulin dependent type II diabetes, insulin resistance, obesity, lipid disorder, metabolic syndrome, and other diseases or condition mediated by the excessive activity of glucocorticoid. |
申请公布号 |
PH12014502802(B1) |
申请公布日期 |
2015.02.09 |
申请号 |
PH2002120145028 |
申请日期 |
2014.12.16 |
申请人 |
BAMICHEM CO., LTD.;INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION;AHN-GOOK PHARMACEUTICAL CO., LTD. |
发明人 |
HAN, CHEOL KYU;AUH, JIN;CHOI, NAM SONG;HAN, CHANG KYUN;KIM, TAE-JEONG;PAE, KAMSA;SHIN, YOUNG JUNE;HAN, DONG-OH;AHN, SOON KIL |
分类号 |
A61K31/18;A61K31/223;A61P3/04;A61P3/10;A61P43/00;C07C303/38;C07C311/12 |
主分类号 |
A61K31/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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