Foot-and-mouth disease virus expressing P1-protective antigen of O-PanAsia-2 strain and the manufacturing methods

摘要

The present invention relates to a recombinant foot-and-mouth virus including plasmid in which a recombinant gene where a gene coding P1 protein which is a protective antigen of foot-and-moth O type vaccine virus strain Manisa is substituted to a gene coding P1 protein which is a protective antigen of foot-and-mouth O-PanAsia-2 genotype series virus is inserted among the entire gene parts of the foot-and-moth O type vaccine virus strain Manisa, and to a manufacturing method thereof.