| 摘要 |
A delayed-release pharmaceutical composition, comprising; an effervescent tablet, granule, or powder containing a first effervescing organic acid component and a first effervescing base component, wherein said tablet granule, or powder is completely solubilized in drinking water at 25 °C within 2 minutes without stirring; and an effective amount of active pharmaceutical ingredient (API) coated with a delayed- release effervescent floating delivery system containing a second effervescing base component, which system is buoyant, in gastric fluid and thus increases gastric retention time (GRT) in a patient. |
