| 发明名称 |
PHARMACEUTICAL COMPOSITIONS OF RANOLAZINE AND DRONEDARONE |
| 摘要 |
The present disclosure relates to a solid composition comprising ranolazine and a spray-dried phosphoric acid salt of dronedarone in a bilayer tablet. |
| 申请公布号 |
US2015037410(A1) |
申请公布日期 |
2015.02.05 |
| 申请号 |
US201414445986 |
申请日期 |
2014.07.29 |
| 申请人 |
Gilead Sciences, Inc. |
发明人 |
Gerber Michael;Huang Neal;Koziara Joanna M.;Zhang Feng |
| 分类号 |
A61K9/24;A61K9/20;A61K47/38;A61K31/343;A61K31/495 |
主分类号 |
A61K9/24 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A bilayer tablet comprising ranolazine and one or more pharmaceutically acceptable excipients in a first layer, and a stable solid spray-dried phosphoric acid salt formulation of dronedarone further comprising HPMC E3 or HPMC E5 and one or more pharmaceutically acceptable excipients in a second layer. |
| 地址 |
Foster City CA US |
