发明名称 HISTAMINE-RELEASING FACTOR (HRF), HRF-RECEPTOR AND METHODS OF MODULATING INFLAMMATION
摘要 Methods of treating a food allergy, allergic reactions, hypersensitivity, inflammatory responses, inflammation are provided. In one method, histamine releasing factor (HRF)/translationally controlled tumor protein (TCTP) is contacted with a compound that inhibits or reduces binding of HRF/TCTP to an immunoglobulin in order to treat the food allergy, allergic reaction, hypersensitivity, inflammatory response, or inflammation. Methods of reducing or decreasing the probability, severity, frequency, duration or preventing a subject from having an acute or chronic food allergy, allergic reaction, hypersensitivity, an inflammatory response or inflammation, are also provided. In one method, histamine releasing factor (HRF)/translationally controlled tumor protein (TCTP) is contacted with a compound that inhibits or reduces binding of HRF/TCTP to an immunoglobulin in order to reduce or decrease the probability, severity, frequency, duration or prevent a subject from having an acute or chronic food allergy, allergic reaction, hypersensitivity, an inflammatory response or inflammation.
申请公布号 US2015037330(A1) 申请公布日期 2015.02.05
申请号 US201414462424 申请日期 2014.08.18
申请人 LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY 发明人 Kawakami Toshiaki;Kawakami Yuko
分类号 C07K16/18;C07K7/08;C07K14/47 主分类号 C07K16/18
代理机构 代理人
主权项 1. (canceled)
地址 La Jolla CA US