NIACIN-PEPTIDE HAVING SKIN WHITENING ACTIVITY AND USE FOR SAME

摘要

Provided is niacin-peptide which has skin whitening activity. The peptide of the present invention has skin whitening activity by inhibiting melanogenesis, that is, by inhibiting the expression of a gene related to melanogenesis (for example, TRP-1, TRP2, or MIFT). The peptide of the present invention has high stability and skin permeability. Also provided is a cosmetic composition for skin whitening which contains the niacin-peptide.

主权项

1. A peptide having skin whitening effect, characterized in that the peptide is selected from the group consisting of Nicotinoyl-PS, Nicotinoyl-EQ, Nicotinoyl-ET, Nicotinoyl-FP, Nicotinoyl-NI, Nicotinoyl-NL, Nicotinoyl-NP, Nicotinoyl-NY, Nicotinoyl-PG, Nicotinoyl-QI, Nicotinoyl-VA, Nicotinoyl-VF, Nicotinoyl-VS, Nicotinoyl-VT, Nicotinoyl-WM, Nicotinoyl-YR, Nicotinoyl-YT, Nicotinoyl-AHK, Nicotinoyl-FWY, Nicotinoyl-GHR, Nicotinoyl-GPHyp, Nicotinoyl-TYR, Nicotinoyl-YGY, Nicotinoyl-PLG, Nicotinoyl-PLG-NH2, Nicotinoyl-beta-AHSH, Nicotinoyl-DKYV, Nicotinoyl-GEPG, Nicotinoyl-GQPR, Nicotinoyl-GRKG, Nicotinoyl-KAKA, Nicotinoyl-SSNA, Nicotinoyl-VPAA, Nicotinoyl-YPFF, Nicotinoyl-YPFF-NH2, Nicotinoyl-GPRPA, Nicotinoyl-GPRPA-NH2, Nicotinoyl-ISELGW, Nicotinoyl-KLAKK, Nicotinoyl-KRGDR, Nicotinoyl-KRGKP, Nicotinoyl-KTTKS, Nicotinoyl-KVARP, Nicotinoyl-RKDVY, Nicotinoyl-YGGFL, Nicotinoyl-YGGFM, Nicotinoyl-SIKVAV, Nicotinoyl-VEPIPY, Nicotinoyl-VGVAPG, Nicotinoyl-EEMQRR, Nicotinoyl-EEMQRR-NH2, Nicotinoyl-GPQGPQ and Nicotinoyl-YGYTGA.