| 发明名称 |
AFUCOSYLATED ANTI-FGFR2IIIB ANTIBODIES |
| 摘要 |
The present invention provides antibodies that bind FGFR2IIIb, wherein the antibodies are afucosylated. The present invention provides compositions comprising antibodies that bind FGFR2IIIb, wherein at least 95% of the antibodies in the composition are afucosylated. In some embodiments, methods of treating cancer comprising administering afucosylated anti-FGFR2IIIb antibodies are provided. |
| 申请公布号 |
WO2015017600(A1) |
申请公布日期 |
2015.02.05 |
| 申请号 |
WO2014US49008 |
申请日期 |
2014.07.31 |
| 申请人 |
FIVE PRIME THERAPEUTICS, INC. |
发明人 |
HARDING, THOMAS;PIERCE, KRISTEN;PATIL, NAMRATA;BRENNAN, THOMAS;HAMBLETON, JULIE |
| 分类号 |
C07K16/28;A61K39/00;A61P35/00 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
