| 发明名称 |
NTRK2 FUSIONS |
| 摘要 |
The invention provides to NTRK ("Neurotrophic Tyrosine Receptor Kinase) gene fusions, NTRK. fosion proteins, and fragments of those genes and polypeptides. The invention further provides methods of diagnosing and treating diseases or disorders associated with NTRK fusions, such as conditions mediated by aberrant NTRK expression or activity, or overexpression of NTRK. |
| 申请公布号 |
WO2015017533(A1) |
申请公布日期 |
2015.02.05 |
| 申请号 |
WO2014US48881 |
申请日期 |
2014.07.30 |
| 申请人 |
BLUEPRINT MEDICINES CORPORATION |
发明人 |
STRANSKY, NICOLAS;CERAMI, ETHAN, G.;LENGAUER, CHRISTOPH |
| 分类号 |
C07K16/40;C12Q1/48;C12Q1/68 |
主分类号 |
C07K16/40 |
| 代理机构 |
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