发明名称 |
Method for obtaining biologically active recombinant human G-CSF |
摘要 |
<p>Provided is a method of obtaining biologically active recombinant human G-CSF from inclusion bodies, wherein the solubilization and refolding process can be performed at ambient temperature and the purification step comprises reversed phase chromatography (RP), in particular RP-HPLC. The G-CSF preparation so obtained is characterized by high purity and homogeneity.</p> |
申请公布号 |
AU2011229491(B2) |
申请公布日期 |
2015.02.05 |
申请号 |
AU20110229491 |
申请日期 |
2011.03.17 |
申请人 |
RATIOPHARM GMBH |
发明人 |
HINDERER, WALTER;SCHECKERMANN, CHRISTIAN |
分类号 |
C07K14/535 |
主分类号 |
C07K14/535 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|