摘要 |
<p>A breath-powered, dry powder inhaler, a cartridge, and a pulmonary drug delivery system are provided. The dry powder inhaler can be provided with or without a unit dose cartridge for using with the inhaler. The inhaler and/or cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, peptides and proteins such as insulin and glucagon-like peptide 1 for the treatment of diabetes and/or obesity. The dry powder inhaler is compact; can be provided in various shapes and sizes, colors, and comprises a housing, a mouthpiece, a cartridge placement area, and a mechanism for opening and closing the medicament cartridge. The device is easy to manufacture, provides a pre-metered single unit dose, it is relatively easy to use, and can be reusable or disposable. WO 20019/152477 PCTJUS2009/047281 0 Ca to to -"</p> |
申请人 |
MANNKIND CORPORATION |
发明人 |
SMUTNEY, CHAD C.;KINSEY, P. SPENCER;SAHI, CARL R.;ADAMO, BENOIT;POLIDORO, JOHN M.;MCLEAN, SCOTT;OVERFIELD, DENNIS;BRYANT, ANTHONY;HE, TOM;MANN, ALFRED |