| 发明名称 |
CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR |
| 摘要 |
The present disclosure relates to crystalline solid forms of [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid, the process of preparing the forms, and pharmaceutical compositions and methods of use thereof. |
| 申请公布号 |
US2015038529(A1) |
申请公布日期 |
2015.02.05 |
| 申请号 |
US201414520232 |
申请日期 |
2014.10.21 |
| 申请人 |
FIBROGEN, INC. |
发明人 |
Witschi Claudia;Park Jung Min;Thompson Michael D.;Martinelli Michael John;Yeowell David A.;Arend Michael P. |
| 分类号 |
C07D217/26 |
主分类号 |
C07D217/26 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for treating, pretreating, or delaying onset or progression of a condition mediated at least in part by hypoxia inducible factor (HIF), comprising administering to a patient in need thereof, a therapeutically effective amount of crystalline [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid (Compound A Form A) characterized by an X-ray powder diffractogram comprising the following peaks: 8.5, 16.2, and 27.4 °2θ±0.2 °2θ. |
| 地址 |
San Francisco CA US |
