| 发明名称 |
AGOMELATINE SULFONIC ACIDS COMPLEXES AND PREPARATION THEREOF |
| 摘要 |
<p>Disclosed are agomelatine sulfonic acids complexes having the specific stoichiometry of 2 molar equivalents of agomelatine for 1 molar equivalent of sulfonic acids. Those complexes show excellent solubility, stability and purity, making them favourable for use in the manufacture of pharmaceutical formulations containing agomelatine.</p> |
| 申请公布号 |
WO2015013865(A1) |
申请公布日期 |
2015.02.05 |
| 申请号 |
WO2013CN80337 |
申请日期 |
2013.07.29 |
| 申请人 |
LES LABORATOIRES SERVIER;SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY |
发明人 |
SHAN, HANBIN;SHEN, YUHUI;LUO, YING;LETELLIER, PHILIPPE;LYNCH, MICHAEL |
| 分类号 |
C07C233/18;A61K31/165;A61K31/185;A61P25/24;C07C309/29;C07C309/35 |
主分类号 |
C07C233/18 |
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