发明名称 FORMULATION OF SYK INHIBITORS
摘要 Disclosed are pharmaceutical compositions comprising a compound having the formula:;;or a pharmaceutically acceptable salt thereof, or a hydrate of thereof, and at least one pharmaceutically acceptable polymer. The pharmaceutically acceptable salt of the compound of Formula I, or a hydrate thereof, can be a mesylate salt, including, for example, a mono-mesylate or a bis-mesylate salt, or a hydrate thereof. Also disclosed are methods of use for the pharmaceutical composition.
申请公布号 US2015038504(A1) 申请公布日期 2015.02.05
申请号 US201414445970 申请日期 2014.07.29
申请人 Gilead Connecticut, Inc. 发明人 CASTEEL Melissa Jean;LI Bei;PAKDAMAN Rowchanak;SPERGER Diana;STEFANIDIS Dimitrios
分类号 C07D487/04;A61K9/20;C07C309/66 主分类号 C07D487/04
代理机构 代理人
主权项 1. A composition comprising: (i) a bis-mesylate salt of a compound of Formula I: or a hydrate thereof, and (ii) at least one pharmaceutically acceptable carrier.
地址 Foster City CA US