发明名称 ENHANCED PRODUCTION OF ISOPRENE USING HOST CELLS HAVING DECREASED ISPA ACTIVITY.
摘要 This invention relates to recombinant microorganisms capable of producing isoprene and isoprene production with the use of such recombinant microorganism with good efficiency. In this invention, functional activity of the ispA gene is altered to reduce the production of isoprenoid molecules in recombinant cells engineered to produce isoprene or in cells otherwise susceptible to isoprenoid accumulation during fermentation. This decreased ispA gene functional activity enables enhanced synthesis of isoprene in a host microorganism.
申请公布号 MX2014007623(A) 申请公布日期 2015.02.04
申请号 MX20140007623 申请日期 2012.12.21
申请人 DANISCO US INC. 发明人 DMITRII V. VAVILINE;JOSEPH C. MCAULIFFE;RACHEL E. MUIR;ALEX T. NIELSEN;CAROLINE M. PERES;DEREK H. WELLS
分类号 C12N9/10;C12P5/00 主分类号 C12N9/10
代理机构 代理人
主权项
地址