发明名称 |
TRIAZINONE COMPOUND AND T-TYPE CALCIUM CHANNEL INHIBITOR. |
摘要 |
[Problem] To provide a novel triazinone compound which has an inhibitory activity on a T-type voltage-dependent calcium channel and is useful particularly for the treatment of pain. [Solution] Provided is a novel triazinone compound represented by formula (I) (wherein each substituent is as defined in detail in the text; R1 represents a hydrogen atom, a C1-6 alkoxy group or the like; L1 and L2 independently represent a single bond, NR2 or the like; L3 represents a C1-6 alkylene group or the like; A represents a C6-14 aryl group which may be substituted, a 5- to 10-membered heteroaryl group or the like; B represents a C3-11 cycloalkylene group or the like; and D represents a C6-14 aryl group which may be substituted, a 5- to 10-membered heteroaryl group or the like), a tautomer or a pharmaceutically acceptable salt of the compound, or a solvate of the compound, the tautomer or the pharmaceutically acceptable salt. |
申请公布号 |
MX2014011721(A) |
申请公布日期 |
2015.02.04 |
申请号 |
MX20140011721 |
申请日期 |
2013.03.29 |
申请人 |
NISSAN CHEMICAL INDUSTRIES, LTD. |
发明人 |
NORIKO SAITO;JUN EGI;HIROSHI NAGAI;MEGUMI UENO;YUSUKE SHINTANI;YUSUKE INABA;MICHIAKI ADACHI;YUICHI HIRAI;TAKESHI KAWAZU;KOICHI YASUTAKE;DAIKI TAKAHASHI |
分类号 |
C07D251/46;A61K31/53;A61K31/5377;A61P25/04;A61P43/00;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D403/04;C07D403/06;C07D403/12;C07D405/06;C07D405/12;C07D409/06;C07D409/12;C07D409/14;C07D413/04;C07D417/06 |
主分类号 |
C07D251/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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