发明名称 | Tailored oils | ||
摘要 | Recombinant DNA techniques are used to produce oleaginous recombinant cells that produce triglyceride oils having desired fatty acid profiles and regiospecific or stereospecific profiles. Genes manipulated include those encoding stearoyl-ACP desturase, delta 12 fatty acid desaturase, acyl-ACP thioesterase, ketoacyl-ACP synthase, and lysophosphatidic acid acyltransferase. The oil produced can have enhanced oxidative or thermal stability, or can be useful as a frying oil, shortening, roll-in shortening, tempering fat, cocoa butter replacement, as a lubricant, or as a feedstock for various chemical processes. The fatty acid profile can be enriched in midchain profiles or the oil can be enriched in triglycerides of the saturated-unsaturated-saturated type. | ||
申请公布号 | US8945908(B2) | 申请公布日期 | 2015.02.03 |
申请号 | US201313865974 | 申请日期 | 2013.04.18 |
申请人 | Solazyme, Inc. | 发明人 | Franklin Scott;Somanchi Aravind;Rudenko George;Bhat Riyaz;Zhao Xinhua;Bond Risha;Rakitsky Walter;Marangoni Alejandro;Braksmayer Diza |
分类号 | C12N1/12;C12P7/64;C12P33/00;A23D9/00;C07C57/03;C07J9/00 | 主分类号 | C12N1/12 |
代理机构 | Alston & Bird LLP | 代理人 | Alston & Bird LLP |
主权项 | 1. An oleaginous microalgal cell of genus Prototheca, the cell comprising an active exogenous KASII (ketoacyl ACP synthase) gene encoding a protein having at least 95% sequence identity to the protein encoded by nucleotides 4039 to 5328 of SEQ ID NO:95 and producing an oil comprising triglycerides, wherein the oil is enriched in stearic-oleic-stearic. | ||
地址 | South San Francisco CA US |