| 发明名称 | Non-aqueous pharmaceutical composition | ||
| 摘要 | A composition for intranasal delivery of a drug comprising: includes: (i) the drug; and (ii) a non-aqueous vehicle containing (a) propylene glycol and at least one additional solvent selected from N-methylpyrrolidone, propylene carbonate, dimethyl sulfoxide and at least one propylene glycol fatty acid ester; (b) from about 40 to 100% by volume of N-methylpyrrolidone; or (c) from about 40 to 100% by volume of dimethyl sulfoxide (DMSO). | ||
| 申请公布号 | US8946208(B2) | 申请公布日期 | 2015.02.03 |
| 申请号 | US200812201226 | 申请日期 | 2008.08.29 |
| 申请人 | Archimedes Development Limited | 发明人 | Castile Jonathan;Smith Alan;Cheng Yu-Hui;Watts Peter James |
| 分类号 | A01N43/62;A61K31/55;C07D243/12;A61K9/00;A61K9/08;A61K31/5517;A61K47/10;A61K47/14;A61K47/22 | 主分类号 | A01N43/62 |
| 代理机构 | Panitch Schwarze Belisario & Nadel LLP | 代理人 | Panitch Schwarze Belisario & Nadel LLP |
| 主权项 | 1. A non-aqueous liquid composition for intranasal delivery of a benzodiazepine drug consisting essentially of: (i) the drug; and (ii) a non-aqueous vehicle consisting essentially of about 30 to 85% v/v propylene glycol and 15 to 70% v/v propylene carbonate, wherein the non-aqueous liquid composition is suitable for delivery in a form of drops or a spray. | ||
| 地址 | Nottingham GB | ||