发明名称 |
Hypoallergenic variants of the major allergen from <i>Betula verrucosa </i>pollen |
摘要 |
The invention provides hypoallergenic variants of Bet v 1 major allergen from Betula verrucosa plant pollen and the use thereof for the preventive or therapeutic treatment of allergic diseases. |
申请公布号 |
US8945574(B2) |
申请公布日期 |
2015.02.03 |
申请号 |
US200612159528 |
申请日期 |
2006.12.19 |
申请人 |
Lofarma S.p.A. |
发明人 |
Mistrello Giovanni;Zanotta Stefania;Roncarolo Daniela;Falagiani Paolo |
分类号 |
A61K38/00;A61K39/00;A61K39/35;C07K1/00;C07K14/00;C07K17/00;C07K14/415;A61K39/36 |
主分类号 |
A61K38/00 |
代理机构 |
Arent Fox LLP |
代理人 |
Arent Fox LLP |
主权项 |
1. A protein which is a hypoallergenic variant of the major allergen of Betula verrucosa pollen (Bet v 1), wherein the protein is selected from the group consisting of SEQ ID NOs: 2-5. |
地址 |
Milan IT |