发明名称 INIBIDORES DNA-PK
摘要 <p>A compound of formula I: wherein: R1 and R2 are independently selected from hydrogen, an optionally substituted C1-7 alkyl group, C3-20 heterocyclyl group, or C5-20 aryl group, or may together form, along with the nitrogen atom to which they are attached, an optionally substituted heterocyclic ring having from 4 to 8 ring atoms; X is CH or N; n is 1 or 2; RC1 and RC2 are independently selected from H and methyl; when X is N, RX is selected from the group consisting of H, and optionally substituted C1-7 alkyl, C3-20 heterocyclyl, C5-20 aryl, acyl, ester, amido and sulfonyl; and when X is CH, RX is selected from the group consisting of H, and optionally substituted C1-7 alkyl, C3-20 heterocyclyl, C5-20 aryl, acyl, ester, amido, sulfonyl, amino and ether.</p>
申请公布号 BRPI0814797(A2) 申请公布日期 2015.02.03
申请号 BR2008PI14797 申请日期 2008.07.18
申请人 KUDOS PHARMACEUTICALS LIMITED;CANCER RESEARCH TECHNOLOGY LTD 发明人 MARK FRIGERIO;MARC GEOFFREY HUMMERSONE;KEITH ALLAN MENEAR;CHRISTINE SARAH BAILEY;HEATHER MARY ELLEN DUGGAN;SYLVIE GOMEZ;NIALL MORRISON BARR MARTIN
分类号 C07D409/04;A61K31/4535;A61K31/497;A61P35/00;C07D409/14 主分类号 C07D409/04
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