发明名称 |
Crystalline forms of a factor Xa inhibitor |
摘要 |
Provided herein are crystalline forms of a maleate salt of betrixaban, compositions and methods of preparation or use thereof. |
申请公布号 |
US8946269(B2) |
申请公布日期 |
2015.02.03 |
申请号 |
US201113223023 |
申请日期 |
2011.08.31 |
申请人 |
Portola Pharmaceuticals, Inc. |
发明人 |
Capodanno Vincent R.;Corcoran Liam;McNevin Michael;Arroyo Itzia Zoraida;Wenslow Robert M.;Ball Richard G.;Margelefsky Eric L.;Maher Timothy K.;Pandey Anjali |
分类号 |
A61K31/44;C07D213/75 |
主分类号 |
A61K31/44 |
代理机构 |
Sheppard Mullin Richter & Hampton LLP |
代理人 |
Sheppard Mullin Richter & Hampton LLP |
主权项 |
1. A crystalline form of betrixaban maleate, which is Form II, having an X-ray powder diffraction pattern having at least the following characteristic peak locations of 10.1, 14.6, 18.0, and 22.0 degrees 2θ (each ±0.1 degrees 2θ). |
地址 |
South San Francisco CA US |