| 发明名称 | Methods and compositions for inhibiting the nuclear factor κB pathway | ||
| 摘要 | The current invention provides therapeutic methods which include inhibition of nuclear factor κb pathway in a cell based on the discovery of an active fraction of a plant extract termed NUP or a composition which includes NUP. NUP is used in treating and managing different diseases such as cancer, inflammation, and virus infections. | ||
| 申请公布号 | US8945632(B2) | 申请公布日期 | 2015.02.03 |
| 申请号 | US201113810668 | 申请日期 | 2011.07.19 |
| 申请人 | Ben Gurion University of the Negev R&D Authority;Mor Research Applications Ltd. | 发明人 | Golan Avi;Gopas Jacob;Ozer Janet;Eisner Nadav;Bacher Adelbert;Eisenreich Wolfgang;Ostrozhenkova Elena;Winer Hila |
| 分类号 | A61K31/24;A61K31/44;A61K31/70;A61K31/438;A61K31/4747;A61K36/62;A61K31/7048;A61K33/24 | 主分类号 | A61K31/24 |
| 代理机构 | Pearl Cohen Zedek Latzer Baratz LLP | 代理人 | Pearl Cohen Zedek Latzer Baratz LLP |
| 主权项 | 1. A method for treating a subject afflicted with Hodgkin lymphoma, melanoma, or lung melanoma, comprising administering to said subject a) a compound of Formula (I) or (II), a composition comprising a fraction of a Nymphaeaceae extract comprising a compound of Formula (I) and a compound of Formula (II); or a combination of the compound of Formula (I) and the compound of Formula (II)and; b) a composition comprising podophyllotoxin drug or platinum drug. | ||
| 地址 | Beer Sheva IL | ||