发明名称 Skin lightening composition for hyperpigmented skin
摘要 An improved skin composition intended for topical application to skin for lightening hyperpigmented skin is provided. The subject composition is characterized by incorporation of at least one carbohydrate-based melanin inhibiting agent selected from bearberry extract, ascorbyl glucoside, rutin and arbutin into an ultra low molecular weight aminoglycan polymer gel. It has been found that the skin composition of the present invention possesses improved skin penetration and significantly enhances the depigmenting effect of the active agents.
申请公布号 US8945523(B2) 申请公布日期 2015.02.03
申请号 US200612521353 申请日期 2006.12.26
申请人 Bomi Patel Framroze 发明人 Patel Framroze Bomi
分类号 A61K8/00;A61K8/18;A61Q5/08;A61Q19/02;A61K8/02;A61K8/73;A61K8/60 主分类号 A61K8/00
代理机构 Westerman, Hattori, Daniels & Adrian, LLP 代理人 Westerman, Hattori, Daniels & Adrian, LLP
主权项 1. A method for lightening hyperpigmented skin in a subject comprising topically administering to the subject in need thereof an effective amount of a composition consisting of arbutin incorporated into hyaluronic acid sodium salt having molecular weight ranging from 15,000 to 30,000 Daltons, and at least one cosmetically acceptable ingredient selected from the group consisting of white beeswax, paraffin wax, emulsifier wax, green tea extract, methylparaben, cetomacrogol 1000, cetostearyl alcohol, disodium hydrogen phosphate, sodium dihydrogen phosphate, propyl paraben, propylene glycol, liquid paraffin, essential oils and water, wherein the arbutin is present in the composition in an amount of from 1 to 20% by weight and the hyaluronic acid sodium salt is present in the composition in an amount of from 1 to 99% by weight.
地址 Toronto CA