| 发明名称 |
Water soluble furoxan derivatives having antitumor activity |
| 摘要 |
Water soluble compounds having a furoxan structure which are capable of inhibiting metabolic pathways involved in the development of the tumours are provided. The use of such compounds as a medicament in the therapy of the tumours and as an adjuvant in the immunotherapy protocols against neoplasms is also described. |
| 申请公布号 |
US8946271(B2) |
申请公布日期 |
2015.02.03 |
| 申请号 |
US201113522026 |
申请日期 |
2011.02.23 |
| 申请人 |
Humanitas Mirasole S.p.A.;Istituto Oncologico Veneto IRCCS |
发明人 |
Viola Antonella;Bronte Enzo;Crosetti Marco;Lazzarato Loretta;Fruttero Roberta;Gasco Alberto |
| 分类号 |
C07D271/08;A61K31/4245 |
主分类号 |
C07D271/08 |
| 代理机构 |
|
代理人 |
Alderson Jr. Robert E. |
| 主权项 |
1. A compound having a formula selected from the group consisting of: and pharmaceutically acceptable salts thereof. |
| 地址 |
Rozzano (MI) IT |
