主权项 |
1. A composition comprising a hydrophilic biologically compatible first polymer, wherein the first polymer is isolated and purified chondroitin sulfate functionalized with an imide group, and at least one second hydrophilic biologically compatible polymer, wherein said second polymer comprises at least one amine group and is capable of reacting with the first polymer, the second polymer being selected from the group consisting of poly(ethylene oxide), partially or fully hydrolyzed poly(vinyl alcohol), polypropylene oxide) block copolymers, poly(vinylpyrrolidone), poly(ethyloxazoline), poly(ethylene oxide)-co-poly(propylene oxide) block copolymers, poloxamines, carboxymethyl cellulose, hydroxyalkylated cellulose, polypeptides, polysaccharides, carbohydrates, polysucrose, dextran, heparin sulphate, keratan sulfate, heparin, alginate, gelatin, collagen, albumin, ovalbumin, poly(phosphoesters), poly(lactides), poly(glycolides), poly(caprolactones), poly(amides), poly(urethanes), poly(esteramides), poly(orthoesters), poly(dioxanones), poly(acetals), poly(ketals), poly(carbonates), poly(orthocarbonates), poly(phosphazenes), poly(hydroxybutyrates), poly(hydroxyl valerates), poly(alkylene oxalates), poly(alkylene succinates), poly(malic acids), polyvinylalcoholpoly(hydroxycellulose), chitin, chitosan, and copolymers, terpolymers or combinations or mixtures thereof. |