主权项 |
1. A peptide of general formula (I)
R1-Wn-Xm-AA1-AA2-AA3-AA4-AA5-AA6-Yp-Zs-R2 (I) its stereoisomers, mixtures thereof and/or its cosmetic or pharmaceutically acceptable salts, wherein:
AA1 is selected from the group consisting of -Asp-, -Glu- and -Pro-;AA2 is -Asp-;AA3 is selected from the group consisting of -Tyr- and -Arg-;AA4 is selected from the group consisting of -Phe- and -Tyr-;AA5 is selected from the group consisting of -Arg- and -Lys-;AA6 is selected from the group consisting of -Leu- and -Met-;W, X, Y and Z are independently selected from amongst themselves from the group consisting of coded amino acids and non-coded amino acids;n, m, p and s are independently selected from amongst themselves and have a value of between 0 and 1;R1 is selected from the group consisting of H, substituted or unsubstituted non-cyclic aliphatic groups, substituted or unsubstituted alicyclyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted heteroarylalkyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl and R5—CO— wherein R5 is selected from the group consisting of H, substituted or unsubstituted non-cyclic aliphatic groups, substituted or unsubstituted alicyclyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl, substituted or unsubstituted heterocyclyl, and substituted or unsubstituted heteroarylalkyl; andR2 is selected from the group consisting of —NR3R4, —OR3 and —SR3, wherein R3 and R4 are independently selected from the group consisting of H, substituted or unsubstituted non-cyclic aliphatic groups, substituted or unsubstituted alicyclyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted heteroarylalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted aralkyl. |