发明名称 AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF
摘要 [Object] To provide a therapeutic and/or prophylactic agent for urinary frequency, urinary urgency, and urinary incontinence associated with various lower urinary tract diseases including overactive bladder, various lower urinary tract diseases accompanied by lower urinary tract pain, such as interstitial cystitis, chronic prostatitis, and the like, and various diseases accompanied by pain, based on an excellent trkA receptor inhibitory action. [Means for Solution] A novel azolecarboxamide compound in which a thiazole ring or an oxazole ring is bonded to a benzene ring, a pyridine ring, a pyridazine ring, a thiophene ring, a pyrazole ring or a pyrrole ring through carboxamide, or a salt thereof is confirmed to have a potent trkA receptor inhibitory activity, and found to be capable of being used as a therapeutic and/or prophylactic agent which is excellent in efficacy and safety for urinary frequency, urinary urgency, and urinary incontinence associated with various lower urinary tract diseases including overactive bladder, various lower urinary tract diseases accompanied by lower urinary tract pain, such as interstitial cystitis, chronic prostatitis, and the like, and various diseases accompanied by pain, thereby completing the present invention.
申请公布号 HRP20140970(T1) 申请公布日期 2015.01.30
申请号 HR2014P000970T 申请日期 2014.10.10
申请人 ASTELLAS PHARMA INC. 发明人 SUGASAWA, KEIZO;KAWAGUCHI, KENICHI;NOMURA, TAKAHO;MATSUMOTO, SHUNICHIRO;SHIN, TAKASHI;AZAMI, HIDENORI;ABE, TOMOAKI;SUGA, AKIRA;SEO, RYUSHI;TANAHASHI, MASAYUKI;WATANABE, TORU
分类号 C07D277/20;A61K31/421;A61K31/422;A61K31/426;A61K31/427;A61K31/4439;A61K31/444;A61K31/454;A61K31/4545;A61K31/5377;A61P13/02;A61P43/00;C07D263/34;C07D263/48;C07D277/56;C07D401/14;C07D413/04;C07D413/12;C07D417/04;C07D417/12;C07D417/14 主分类号 C07D277/20
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