发明名称 |
METHOD FOR DIAGNOSING CANCERS EXPRESSING A TRUNCATED HER2 RECEPTOR VARIANT |
摘要 |
<p>The present invention relates to a method of diagnosis and therapy of cancers expressing the HER2 receptor. The invention provides antibodies or fragments thereof that recognizes an epitope of a HER2 receptor truncated form, said epitope being defined by a sequence included in SEQ ID NO: 2. The invention also provides a method of cancer diagnosis, which comprises the detection of the presence of the HER2 receptor truncated form consisting of the amino acid sequence SEQ ID NO: 1 in a patient sample.</p> |
申请公布号 |
SI2293819(T1) |
申请公布日期 |
2015.01.30 |
申请号 |
SI20090031079T |
申请日期 |
2009.06.05 |
申请人 |
FUNDACIO PRIVADA INSTITUT DE RECERCA HOSPITAL UNIVERSITARI VALL HELBRON;FUNDACIO PRIVADA INSTITUCIO CATALANA DE RECERCA IESTUDIS AVANCANTS;FUNDACIO PRIVADA INSTITUT D'INVESTIGACIO ONCOLOGICA DE VALL-HEBRON |
发明人 |
ARRIBAS LOPEZ JOAQUIN;PEDERSEN KIM;ANGELLINI PIER-DAVIDE;PARRA PALAU JOSEP LLUIS;LAOS SIRLE;BASELGA TORRES JOSE |
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