发明名称 |
THIENOPYRIDONE DERIVATIVES AS AMP-ACTIVATED PROTEIN KINASE (AMPK) ACTIVATORS |
摘要 |
The present invention relates to compounds of formula (I) wherein R, Rand B, Bare as defined herein, including pharmaceutical compositions thereof and for their use in the treatment and/or prevention of diseases and disorders modulated by AMP agonists. The invention is also directed to a novel intermediate of formula (II) and to a method of preparation of compounds of formula (I).Formula (I)Formula (II) |
申请公布号 |
EA020773(B1) |
申请公布日期 |
2015.01.30 |
申请号 |
EA20100001733 |
申请日期 |
2009.04.08 |
申请人 |
MERCK PATENT GMBH |
发明人 |
CRAVO DANIEL;LEPIFRE FRANCK;HALLAKOU-BOZEC SOPHIE;CHARON CHRISTINE |
分类号 |
C07D333/38;A61P3/04;A61P3/10;A61P29/00;A61P35/00;C07D495/04 |
主分类号 |
C07D333/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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