发明名称 QUINAZOLINE COMPOUNDS AND THEIR USE IN THERAPY
摘要 This invention relates to quinazoline compounds of Formula (I) which are inhibitors of the histone lysine methyltransferase (HKMTase) EZH2, and to uses of such compounds as medicaments, in particular in the treatment of a disease or disorder in which inhibition of EZH2 provides a therapeutic or prophylactic effect.
申请公布号 EP2828250(A1) 申请公布日期 2015.01.28
申请号 EP20130721004 申请日期 2013.03.19
申请人 IMPERIAL INNOVATIONS LIMITED;EMORY UNIVERSITY 发明人 BROWN, ROBERT;FUCHTER, MATTHEW JOHN;CHAPMAN-ROTHE, NADINE;SRIMONGKOLPITHAK, NITIPOL;CARON, JOACHIM;SNYDER, JAMES P;GANESH, THOTA;LIU, JIN;SUN, AIMING
分类号 C07D401/14;A61K31/517;A61P25/28;A61P31/18;A61P35/00;C07D239/95;C07D401/12;C07D405/14;C07D491/056 主分类号 C07D401/14
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