This invention relates to quinazoline compounds of Formula (I) which are inhibitors of the histone lysine methyltransferase (HKMTase) EZH2, and to uses of such compounds as medicaments, in particular in the treatment of a disease or disorder in which inhibition of EZH2 provides a therapeutic or prophylactic effect.
申请公布号
EP2828250(A1)
申请公布日期
2015.01.28
申请号
EP20130721004
申请日期
2013.03.19
申请人
IMPERIAL INNOVATIONS LIMITED;EMORY UNIVERSITY
发明人
BROWN, ROBERT;FUCHTER, MATTHEW JOHN;CHAPMAN-ROTHE, NADINE;SRIMONGKOLPITHAK, NITIPOL;CARON, JOACHIM;SNYDER, JAMES P;GANESH, THOTA;LIU, JIN;SUN, AIMING