| 发明名称 |
ANTI-CANCER COMPOUNDS TARGETING RAL GTPASES AND METHODS OF USING THE SAME |
| 摘要 |
<p>The invention provides methods of inhibiting the growth or metastasis of a cancer in a mammal by inhibiting a Ral GTPase in the mammal. The invention also provides small molecule inhibitors of Ral GTPases useful in the methods of the invention and pharmaceutical compositions containing the therapeutically effective compounds of the invention, and methods of using the same.</p> |
| 申请公布号 |
KR20150010696(A) |
申请公布日期 |
2015.01.28 |
| 申请号 |
KR20147020271 |
申请日期 |
2012.12.21 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF COLORADO;INDIANA UNIVERSITY RESEARCH &TECHNOLOGY CORPORATION;UNIVERSITY OF VIRGINIA PATENT FOUNDATION |
发明人 |
THEODORESCU DAN;WEMPE MICHAEL FITZPATRICK;ROSS DAVID;MEROUEH SAMY;SCHWARTZ MARTIN A;REIGAN PHILLIP |
| 分类号 |
A61K31/4162;A61K31/4188;A61P35/00 |
主分类号 |
A61K31/4162 |
| 代理机构 |
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