发明名称 Hybrid and tandem expression of neisserial derived proteins
摘要 Two or more Neisserial proteins are joined such that they are translated as a single polypeptide chain. Hybrid proteins are represented by the formula NH 2 -A-[-X-L-] n -B-COOH where X is an amino acid sequence, L is an optional linker amino acid sequence, A is an optional N-terminal amino acid sequence, B is an optional C-terminal amino acid sequence, and n is an integer greater than 1. Proteins where each of the n -X- moieties shares sequence identity to each other -X- moiety, the protein is a 'tandem protein'.
申请公布号 EP2829549(A2) 申请公布日期 2015.01.28
申请号 EP20140172613 申请日期 2002.09.06
申请人 NOVARTIS VACCINES AND DIAGNOSTICS S.R.L. 发明人 PIZZA, MARIAGRAZIA
分类号 C07K14/22;C12N15/09;A61K38/16;A61K39/00;A61K39/08;A61K39/085;A61K39/09;A61K39/095;A61K39/102;A61K39/106;A61K39/118;A61K39/13;A61K39/145;A61K39/165;A61K39/205;A61K39/29;C07H21/00;C07K14/195;C07K19/00;C12N15/10;C12N15/62 主分类号 C07K14/22
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