发明名称 FUSION PROTEIN COMPRISING ALBUMIN AND A RETINOL-BINDING PROTEIN
摘要 The present invention relates to a fusion protein comprising albumin and a retinol-binding protein, which is useful in preventing or treating fibrotic diseases. The fusion protein, in which albumin and a retinol-binding protein (RBP) are bound together, induces the formation of cytoplasmic lipid droplets in stellate cells and returns the shape of activated stellate cells and returns the shape of activated stellate cells to the previous shape thereof before activation. Therefore, the fusion protein of the present invention may be effectively used in preventing or treating fibrotic diseases occurring in liver, pancreas, lungs or the like.
申请公布号 EP2682406(A4) 申请公布日期 2015.01.28
申请号 EP20120752190 申请日期 2012.02.28
申请人 KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION 发明人 OH, JUN SEO
分类号 C07K19/00;A61K38/38;C07K14/76;C12N15/62;C12N15/63 主分类号 C07K19/00
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