发明名称 CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID-DEHYDROGENASE 1
摘要 FIELD: medicine, pharmaceutics.SUBSTANCE: invention relates to compound of formula (Ip)or (Ip)or its pharmaceutically acceptable salt, where Grepresents (C-C)alkyl, (C-C)alkoxy, (C-C)halogenalkyl, (C-C)halogenalkoxy, halogen, cyano or nitro; n equals 0; Grepresents (C-C)cycloalkyl or (C-C)cycloalkyl(C-C)alkyl; Grepresents hydrogen; Rrepresents methyl or ethyl; Rrepresents phenyl or fluorophenyl; and Rrepresents 2-hydroxy-2-methylpropyl or 2-methyl-2-cyanopropyl.EFFECT: invention relates to application of compound of formula (Ipand Ip) for manufacturing medication or pharmaceutical composition, intended for treating a person with disease or state, selected from type II diabetes mellitus, obesity, glucose intolerance, hyperglycemias, hyperlipidemis, insulin resistance, decrease of cognitive functions and dyslipidemia.5 cl, 6 tbl, 107 ex
申请公布号 RU2539979(C2) 申请公布日期 2015.01.27
申请号 RU20110106374 申请日期 2009.07.23
申请人 VAJTAI FARMAS'JUTIKLZ, INK.;BERINGER INGEL'KHAJM INTERNEHSHNL GMBKH 发明人 KHIMMEL'SBAKH FRANK;KLERMON DEHVID A.;CHZHUAN LINKHAN;LEFTERIS KATERINA;SJUJ CHZHEHN'RON;TAJS KOLIN M.
分类号 C07D413/10;A61K31/5355;C07D413/14 主分类号 C07D413/10
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