发明名称 |
FARMACEUTISK PRÆPARAT, DER INDEHOLDER EN OPTISK AKTIV FORBINDELSE MED TROMBOPOIETINRECEPTORAGONIST-AKTIVITET OG ET MELLEMPRODUKT DERAF |
摘要 |
<p>An optically active 4-phenylthiazole derivative having a thrombopoietin receptor agonist activity and a pharmaceutical composition containing the present compound as an active ingredient are created, and a platelet production regulating agent which can be orally administered is provided. Disclosed is a pharmaceutical composition containing, as an active ingredient, an optically active compound represented by the formula:
wherein, R 1 is a halogen atom or C1-C3 alkyloxy; R 2 is C1-C8 alkyl R 3 is C1-C8 alkyl R 4 and R 5 are each independently a fluorine atom or chlorine atom; R 6 is C1-C3 alkyl or C1-C3 alkyloxy * indicates that a carbon atom marked with an asterisk is an asymmetric carbon,
a pharmaceutically acceptable salt thereof, or a solvate thereof.</p> |
申请公布号 |
DK2184279(T3) |
申请公布日期 |
2015.01.26 |
申请号 |
DK20080791776T |
申请日期 |
2008.07.29 |
申请人 |
SHIONOGI&CO., LTD. |
发明人 |
TAKAYAMA, MASAMI;KUROSE, NORIYUKI |
分类号 |
C07D277/20;A61K31/426;A61P1/18;A61P7/00;A61P7/06;A61P43/00;C07D277/46 |
主分类号 |
C07D277/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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