NEW CHALCONE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF HAVING INHIBITORY ACTIVITY ON HSP90 AND MEDICAL USE THEREOF

摘要

The present invention relates to a novel chalcone compound or pharmaceutically acceptable salt thereof having inhibitory activity on Hsp90, and to medical use thereof. The charcone compound: has an excellent effect of inhibiting Hsp90; induces decomposition of Hsp90 client protein, which causes cancer or neurodegenerative diseases; and thus can be advantageously used for a pharmaceutical product or health-promotional food for treating or preventing Hsp90-mediated diseases such as cancer or neurodegenerative diseases. The chalcone compound or the pharmaceutically acceptable salt is represented by Chemical Formula 1 below.