发明名称 FLUORIDE-RESPONSIVE RIBOSWITCHS, FLUORIDE TRANSPORTERS, AND METHODS OF USE
摘要 Disclosed are compounds, compositions, and methods relating to fluoride aptamers, fluoride-responsive riboswitches, fluoride-regulated expression constructs, fluoride transporters, nucleic acids encoding fluoride transporters, expression constructs encoding fluoride transporters, and cells containing or including any combination of these.
申请公布号 US2015023889(A1) 申请公布日期 2015.01.22
申请号 US201214344006 申请日期 2012.09.17
申请人 Yale University 发明人 Breaker Ronald;Baker Jenny;Sudarsan Narasimhan;Weinberg Zasha;Roth Adam;Ames Tyler;Nelson James
分类号 C12N15/115;A61K31/381;A61K31/4436;A23L1/30;A61K45/06;C12Q1/18;C11D3/48;B01D15/38;A61K31/55;A61K31/166 主分类号 C12N15/115
代理机构 代理人
主权项 1. A fluoride aptamer nucleic acid molecule comprising a fluoride aptamer, wherein (a) the nucleic acid molecule further comprises one or more sequences heterologous to the fluoride aptamer, (b) a heterologous component is conjugated to the nucleic acid molecule, or (c) both.
地址 New Haven CT US