发明名称 |
FLUORIDE-RESPONSIVE RIBOSWITCHS, FLUORIDE TRANSPORTERS, AND METHODS OF USE |
摘要 |
Disclosed are compounds, compositions, and methods relating to fluoride aptamers, fluoride-responsive riboswitches, fluoride-regulated expression constructs, fluoride transporters, nucleic acids encoding fluoride transporters, expression constructs encoding fluoride transporters, and cells containing or including any combination of these. |
申请公布号 |
US2015023889(A1) |
申请公布日期 |
2015.01.22 |
申请号 |
US201214344006 |
申请日期 |
2012.09.17 |
申请人 |
Yale University |
发明人 |
Breaker Ronald;Baker Jenny;Sudarsan Narasimhan;Weinberg Zasha;Roth Adam;Ames Tyler;Nelson James |
分类号 |
C12N15/115;A61K31/381;A61K31/4436;A23L1/30;A61K45/06;C12Q1/18;C11D3/48;B01D15/38;A61K31/55;A61K31/166 |
主分类号 |
C12N15/115 |
代理机构 |
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代理人 |
|
主权项 |
1. A fluoride aptamer nucleic acid molecule comprising a fluoride aptamer, wherein (a) the nucleic acid molecule further comprises one or more sequences heterologous to the fluoride aptamer, (b) a heterologous component is conjugated to the nucleic acid molecule, or (c) both. |
地址 |
New Haven CT US |