发明名称 CYANOTRIAZOLE COMPOUNDS
摘要 This invention relates to a cyanotriazole compound represented by the formula (1):, wherein each symbols are defined in the specification, or a salt thereof. The compound or a salt thereof stimulates the citric acid cycle activity and/or improves hyperglycemia with less side effects, and excellent safety, and therefore, it is useful for treating and/or preventing diseases or disorders on which citric acid cycle activation and/or improvement of hyperglycemia has a prophylactic and/or therapeutic effect, for example, diabetes, impaired glucose tolerance, insulin resistance, diabetic complications, obesity, dyslipidemia, hepatic steatosis, atherosclerosis and/or cardiovascular disease, as well as diseases or disorders that would benefit from stimulating energy expenditure.
申请公布号 WO2015008872(A1) 申请公布日期 2015.01.22
申请号 WO2014JP69501 申请日期 2014.07.16
申请人 OTSUKA PHARMACEUTICAL CO., LTD. 发明人 SATO, SEIJI;MATSUDA, SATOSHI;MATSUMURA, CHIHARU;ITOTANI, MOTOHIRO;SHINOHARA, TOSHIO;FUJITA, SHIGEKAZU;SAKURAI, YOHJI;TAI, KUNINORI;FUKUSHIMA, TAE;KANEMOTO, NAOHIDE;OKAMOTO, TAKASHI
分类号 C07D403/12;A61K31/4192;C07D249/04;C07D249/06;C07D401/12;C07D401/14;C07D403/14;C07D405/12;C07D405/14;C07D411/12;C07D411/14;C07D413/12;C07D413/14;C07D417/12;C07D417/14 主分类号 C07D403/12
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