发明名称 |
CYANOTRIAZOLE COMPOUNDS |
摘要 |
This invention relates to a cyanotriazole compound represented by the formula (1):, wherein each symbols are defined in the specification, or a salt thereof. The compound or a salt thereof stimulates the citric acid cycle activity and/or improves hyperglycemia with less side effects, and excellent safety, and therefore, it is useful for treating and/or preventing diseases or disorders on which citric acid cycle activation and/or improvement of hyperglycemia has a prophylactic and/or therapeutic effect, for example, diabetes, impaired glucose tolerance, insulin resistance, diabetic complications, obesity, dyslipidemia, hepatic steatosis, atherosclerosis and/or cardiovascular disease, as well as diseases or disorders that would benefit from stimulating energy expenditure. |
申请公布号 |
WO2015008872(A1) |
申请公布日期 |
2015.01.22 |
申请号 |
WO2014JP69501 |
申请日期 |
2014.07.16 |
申请人 |
OTSUKA PHARMACEUTICAL CO., LTD. |
发明人 |
SATO, SEIJI;MATSUDA, SATOSHI;MATSUMURA, CHIHARU;ITOTANI, MOTOHIRO;SHINOHARA, TOSHIO;FUJITA, SHIGEKAZU;SAKURAI, YOHJI;TAI, KUNINORI;FUKUSHIMA, TAE;KANEMOTO, NAOHIDE;OKAMOTO, TAKASHI |
分类号 |
C07D403/12;A61K31/4192;C07D249/04;C07D249/06;C07D401/12;C07D401/14;C07D403/14;C07D405/12;C07D405/14;C07D411/12;C07D411/14;C07D413/12;C07D413/14;C07D417/12;C07D417/14 |
主分类号 |
C07D403/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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