发明名称 |
Methods for the purification of deoxycholic acid |
摘要 |
Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-α-hydroxysteroids from &Dgr;-9,11-ene, 11-keto or 11-hydroxy-&bgr;-steroids. This invention is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone. |
申请公布号 |
AU2010330760(B2) |
申请公布日期 |
2015.01.22 |
申请号 |
AU20100330760 |
申请日期 |
2010.12.17 |
申请人 |
KYTHERA BIOPHARMACEUTICALS, INC. |
发明人 |
MORIARTY, ROBERT M.;REID, JOHN GREGORY;SWARINGEN JR., ROY A. |
分类号 |
C07J1/00;C07J5/00;C07J9/00;C07J13/00;C07J41/00 |
主分类号 |
C07J1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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