| 发明名称 |
PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIMIDINES |
| 摘要 |
This invention relates to an improved process of making compounds of Formula (I) and synthetic intermediates thereof. (I) In particular, the invention relates to an improved process to prepare N-(2-aminophenyl)-4- ((pyrimidin-2-ylamino)methyl)benzamides which requires fewer steps, is efficient, can be used on an industrial scale, and results in a final product which is suitable for pharmaceutical use. |
| 申请公布号 |
WO2015006875(A1) |
申请公布日期 |
2015.01.22 |
| 申请号 |
WO2014CA50684 |
申请日期 |
2014.07.18 |
| 申请人 |
METHYLGENE INC. |
发明人 |
RAEPPEL, STEPHANE;ZHOU, ZHIHONG;GAUDETTE, FREDERIC;LLEWELLYN, DAVID;VAISBURG, ARKADII;DELORME, DAVID;RAEPPEL, FRANCK;GRANGER, MARIE-CLAUDE;ROY, SIMON |
| 分类号 |
C07D401/04;A61K31/4406;A61K31/506;C07C279/14;C07D213/50 |
主分类号 |
C07D401/04 |
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