ISOLATION, IDENTIFICATION, AND USES OF ANTIFUNGAL COMPOUNDS

摘要

In one aspect, the invention relates to isolated compounds useful as antifungal agents, for example, compounds having a structure represented by a formula: wherein R1 is hydrogen or hydroxyl; wherein R2 is hydrogen, a-xylose or β-xylose; and wherein R3 and R4 are each hydrogen or together oxygen, or a pharmaceutically acceptable salt thereof; methods of isolating and purifying same; pharmaceutical compositions comprising same; agricultural compositions comprising same; and methods of treating and/or preventing fungal infections using same. In one aspect, R2 is not hydrogen or β-xylose when R1 is hydroxyl and R3 and R4 are together oxygen. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

主权项

1. An isolated compound having a structure represented by a formula: wherein R1 is hydrogen or hydroxyl; wherein R2 is hydrogen, α-xylose or β-xylose; and wherein R3 and R4 are each hydrogen or are together oxygen, wherein R2 is not hydrogen or β-xylose when R1 is hydroxyl and R3 and R4 are together oxygen; or a pharmaceutically acceptable salt thereof.