PATULETIN A POTENT ANTI-TNF-a AND ANTI-ARTHRITIC COMPOUND FROM TAGETES PATULA

摘要

Patuletin, a flavonoid isolated from Tagetes patula, was discovered to be a potent inhibitor of TNF-α production and thus useful in treating diseases related to TNF-α levels in the body.

主权项

1. Use of Patuletin or a stereoisomer, or a pharmaceutically acceptable salt, ester, or solvate thereof, in the manufacture of a medicament for the treatment of a disease or disorder, which is mediated by TNF-alpha activity.