| 发明名称 |
NANOFLUIDIC CHANNELS WITH GRADUAL DEPTH CHANGE FOR REDUCING ENTROPIC BARRIER OF BIOPOLYMERS |
| 摘要 |
A device for passing a biopolymer molecule includes a nanochannel formed between a surface relief structure, a patterned layer forming sidewalls of the nanochannel and a sealing layer formed over the patterned layer to encapsulate the nanochannel. The surface relief structure includes a three-dimensionally rounded surface that reduces a channel dimension of the nanochannel at a portion of nanochannel and gradually increases the dimension along the nanochannel toward an opening position, which is configured to receive a biopolymer. |
| 申请公布号 |
US2015021187(A1) |
申请公布日期 |
2015.01.22 |
| 申请号 |
US201313944552 |
申请日期 |
2013.07.17 |
| 申请人 |
INTERNATIONAL BUSINESS MACHINES CORPORATION |
发明人 |
Lin Qinghuang;Stolovitzky Gustavo A.;Wang Chao;Wang Deqiang |
| 分类号 |
B01L3/00;G01N27/447 |
主分类号 |
B01L3/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A device for passing a biopolymer molecule, comprising:
a nanochannel formed between a surface relief structure, a patterned layer forming sidewalls of the nanochannel and a sealing layer formed over the patterned layer to encapsulate the nanochannel; the surface relief structure including a three-dimensionally rounded surface that reduces a channel dimension of the nanochannel at a portion of nanochannel and gradually increases the dimension along the nanochannel toward an opening position, which is configured to receive a biopolymer. |
| 地址 |
Armonk NY US |
