发明名称 Xenoantigen-Displaying Anti-Cancer Vaccines and Method of Making
摘要 Compositions, methods of making, and methods of using, xenoantigen-displaying anticancer vaccines are described. In another broad aspect, there is provided herein a method of synthesizing an alkynefunctionalized composition of claim 1, comprising: deprotecting an ester comprising a Fmoc moiety to form a free acid; coupling the free acid of step (a) with an amine; and, removing the Fmoc moiety, and coupling the remaining moiety with palmitic acid to yield an alkyne-functionalized composition.
申请公布号 US2015024037(A1) 申请公布日期 2015.01.22
申请号 US201314378805 申请日期 2013.02.15
申请人 THE UNIVERSITY OF TOLEDO 发明人 Sucheck Steven J.;Wall Katherine A.;Sarkar Sourav
分类号 A61K39/00;C07K14/705;A61K47/48;C07K7/08;C07K14/47;A61K9/127;C07C323/60;C07K7/06 主分类号 A61K39/00
代理机构 代理人
主权项 1. A composition comprising a first lipid (lipida) moiety and an alkyne amide moiety having a Formula IV:
地址 Toledo OH US