| 发明名称 |
Cell Lines That Produce Prostaglandin F2 Alpha (PGF2A) And Uses Thereof |
| 摘要 |
Cells and cell lines that are genetically modified to express the hCox-2 enzyme, which results in the upregulation of prostaglandin F2 alpha (PGF2a) on the cells have been obtained. Encapsulated cell therapy devices containing such cells or cell lines that are capable of delivering PGF2a, as well as methods of using these devices to deliver PGF2a to the eye and to treat ophthalmic disorders in patients suffering therefrom are also described. |
| 申请公布号 |
US2015024024(A1) |
申请公布日期 |
2015.01.22 |
| 申请号 |
US201013265312 |
申请日期 |
2010.04.21 |
| 申请人 |
Tao Weng;Kauper Konrad;Stabila Paul Francis;Ling Vincent |
发明人 |
Tao Weng;Kauper Konrad;Stabila Paul Francis;Ling Vincent |
| 分类号 |
A61K9/48;A61K35/30;A61K38/18 |
主分类号 |
A61K9/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An expression vector comprising the nucleic acid sequence of SEQ ID NO:1. |
| 地址 |
Lincoln RI US |
