发明名称 |
SPECIFIC NUCLEIC ACID AMPLIFICATION WITH COMPOUNDED SELECTIVITY |
摘要 |
The present disclosure provides, in various aspects and embodiments, methods and compositions for selectively amplifying a rare target nucleic acid and/or suppressing amplification of non-target nucleic acids with sequences similar to the rare target nucleic acid. The methods and composition are useful, for example, for detecting rare alleles among a population of wild-type alleles. |
申请公布号 |
CA2917627(A1) |
申请公布日期 |
2015.01.22 |
申请号 |
CA20142917627 |
申请日期 |
2014.07.18 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
CHEN, XI;ZHANG, DAVID YU;YIN, PENG |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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